| 68-pin M/X-Series Line Name | 68-pin M/X-Series Pin Number | 50-pin Breakout Connector Pin Number |
| AIGND | 24, 27, 29, 32, 56, 59, 64, 67 | 1, 2 |
| AI 0 | 68 | 3 |
| AI 8 | 34 | 4 |
| AI 1 | 33 | 5 |
| AI 9 | 66 | 6 |
| AI 2 | 65 | 7 |
| AI 10 | 31 | 8 |
| AI 3 | 30 | 9 |
| AI 11 | 63 | 10 |
| AI 4 | 28 | 11 |
| AI 12 | 61 | 12 |
| AI 5 | 60 | 13 |
| AI 13 | 26 | 14 |
| AI 6 | 25 | 15 |
| AI 14 | 58 | 16 |
| AI 7 | 57 | 17 |
| AI 15 | 23 | 18 |
| AISENSE | 62 | 19 |
| AO 0 | 22 | 20 |
| AO 1 | 21 | 21 |
| APFI 0 | 20 | 22 |
| AOGND | 54,55 | 23 |
| PFI 15/P2.7 | 39* | 33, 24* |
| P0.0 | 52** | 25 |
| P0.4 | 19** | 26 |
| P0.1 | 17** | 27 |
| P0.5 | 51 | 28 |
| P0.2 | 49** | 29 |
| P0.6 | 16 | 30 |
| P0.3 | 47 | 31 |
| P0.7 | 48 | 32 |
| DGND | 4, 7, 9, 12, 13, 15, 18, 35, 36, 44, 50, 53 | 33, 24* |
| +5V | 8,14 | 34 |
| +5V | 8,14 | 35 |
| PFI 11/P2.3 | 46 | 36 |
| PFI 10/P2.2 | 45 | 37 |
| PFI 0/P1.0 | 11 | 38 |
| PFI 1/P1.1 | 10 | 39 |
| PFI 2/P1.2 | 43 | 40 |
| PFI 3/P1.3 | 42 | 41 |
| PFI 4/P1.4 | 41 | 42 |
| PFI 13/P2.5 | 40 | 43 |
| PFI 5/P1.5 | 6 | 44 |
| PFI 6/P1.6 | 5 | 45 |
| PFI 7/P1.7 | 38 | 46 |
| PFI 8/P2.0 | 37 | 47 |
| PFI 9/P2.1 | 3 | 48 |
| PFI 12/P2.4 | 2 | 49 |
| PFI 14/P2.6 | 1 | 50 |
*For M Series and X Series boards PFI 15 (P2.7) can no longer be used as a digital line. It is tied to digital ground inside the SCXI-1349 module. This occurred a result of the differences between E and M series pinouts.
**These digital resources are used automatically by DAQmx when the DAQ card is controlling an SCXI Chassis. P0.4 is always high when connected to a SCXI-1349
Note: The breakout connector on the SCXI-1346 and SCXI-1349 is only intended for use with the SCXI-1180 Feedthrough Panel